BRIP1 Antikörper (BRCA1 Interacting Protein C-terminal Helicase 1) (pThr1133)

Details for Product anti-BRIP1 Antibody No. ABIN6268184
Target
Bindungsspezifität
pThr1133
16
15
10
8
8
6
4
3
3
2
1
1
1
Reaktivität
Human
64
13
3
1
Wirt
Kaninchen
57
8
1
Klonalität
Polyklonal
Konjugat
Dieser BRIP1 Antikörper ist unkonjugiert
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
46
27
13
8
7
5
3
2
2
1
1
Optionen
Immunogen A synthesized peptide derived from human BACH1/BRIP1 around the phosphorylation site of Thr1133
Isotyp IgG
Spezifität Phospho-BACH1/BRIP1 (Thr1133) Antibody detects endogenous levels of BACH1/BRIP1 only when phosphorylated at Thr1133
Kreuzreaktivität Human
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung BACH1/BRIP1 (BRIP1 Antibody Abstract)
Hintergrund

Description: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

Gene: BRIP1

Molekulargewicht 145kDa
Gen-ID 83990
UniProt Q9BX63
Pathways DNA Reparatur
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) (pThr1133) antibody (ABIN6268184) Western blot analysis of Phospho-BACH1/BRIP1 (Thr1133) in lysates of Jurkat?, using P...