GRF2 Antikörper (Rap Guanine Nucleotide Exchange Factor (GEF) 1) (pThr1071)

Details for Product anti-RAPGEF1 Antibody No. ABIN6268144
Target
Bindungsspezifität
pThr1071
2
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
34
6
5
4
3
3
3
3
2
1
1
1
1
1
Wirt
Kaninchen
24
8
2
Klonalität
Polyklonal
Konjugat
Dieser GRF2 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
21
15
8
6
5
4
1
1
1
Optionen
Immunogen A synthesized peptide derived from human RapGEF1 around the phosphorylation site of Thr1071
Isotyp IgG
Spezifität RapGEF1 (Phospho-Thr1071) Antibody detects endogenous levels of RapGEF1 only when phosphorylated at Thr1071
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung RapGEF1 (RAPGEF1 Antibody Abstract)
Hintergrund

Description: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Gene: RAPGEF1

Molekulargewicht 121kDa
Gen-ID 2889
UniProt Q13905
Pathways Interferon-gamma Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1) (pThr1071) antibody (ABIN6268144) Western blot analysis of RapGEF1 (Phospho-Thr1071) in lysates of HeLa?, using RapGEF1...