MCL-1 Antikörper (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (pSer64)

Details for Product anti-MCL1 Antibody No. ABIN6268120
Target
Bindungsspezifität
pSer64
24
22
18
16
15
14
12
12
8
8
7
5
5
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
201
114
94
8
8
7
5
2
1
1
1
Wirt
Kaninchen
180
18
9
1
Klonalität
Polyklonal
Konjugat
Dieser MCL-1 Antikörper ist unkonjugiert
15
11
11
6
6
6
6
4
4
4
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
160
93
84
28
26
24
23
16
13
6
4
3
2
2
1
Optionen
Immunogen A synthesized peptide derived from human Mcl-1 around the phosphorylation site of Ser64
Isotyp IgG
Spezifität Phospho-Mcl-1 (Ser64) Antibody detects endogenous levels of Mcl-1 only when phosphorylated at Ser64
Kreuzreaktivität Human
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung Mcl-1 (MCL1 Antibody Abstract)
Hintergrund

Description: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Gene: MCL1

Molekulargewicht 40kDa
Gen-ID 4170
UniProt Q07820
Pathways MAPK Signalweg
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (pSer64) antibody (ABIN6268120) Western blot analysis of Phospho-Mcl-1 (Ser64) in lysates of KARPAS-299, using Phosph...