Rpt6 (pSer120) Antikörper

Details zu Produkt Nr. ABIN6268112
Target
Bindungsspezifität
pSer120
7
Reaktivität
Human, Maus, Ratte
8
8
8
Wirt
Kaninchen
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
3
2
1
1
Optionen
Immunogen A synthesized peptide derived from human Rpt6 around the phosphorylation site of S120
Isotyp IgG
Spezifität Phospho-Rpt6 (S120) Antibody detects endogenous levels of Rpt6 only when phosphorylated at S120
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Hintergrund

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Gene: PSMC5

Molekulargewicht 46kDa
Gen-ID 5705
UniProt P62195
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Rpt6 (pSer120) antibody (ABIN6268112) Western blot analysis of Phospho-Rpt6 (S120) in lysates of 293T, using Phospho-Rpt6 (...