VAV2 Antikörper (Vav 2 Guanine Nucleotide Exchange Factor) (pTyr142)

Details for Product anti-VAV2 Antibody No. ABIN6268100
Target
Bindungsspezifität
pTyr142
6
4
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
61
34
25
Wirt
Kaninchen
47
8
3
3
Klonalität
Polyklonal
Konjugat
Dieser VAV2 Antikörper ist unkonjugiert
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
42
23
17
14
13
7
7
4
4
3
2
1
Optionen
Immunogen A synthesized peptide derived from human VAV2 around the phosphorylation site of Tyr142
Isotyp IgG
Spezifität VAV2 (Phospho-Tyr142) Antibody detects endogenous levels of VAV2 only when phosphorylated at Tyr142
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung VAV2 (VAV2 Antibody Abstract)
Hintergrund

Description: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).

Gene: VAV2

Molekulargewicht 101kDa
Gen-ID 7410
UniProt P52735
Pathways Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (pTyr142) antibody (ABIN6268100) Western blot analysis of VAV2 (Phospho-Tyr142) in lysates of K562 TNF 200ng/ml, 30mi...