NUMB Antikörper (Numb Homolog) (pSer276)

Details for Product anti-NUMB Antibody No. ABIN6268078
Target
Bindungsspezifität
pSer276
16
15
15
5
4
4
4
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
83
59
38
6
4
4
4
3
3
2
1
1
1
1
1
1
1
Wirt
Kaninchen
71
13
7
2
Klonalität
Polyklonal
Konjugat
Dieser NUMB Antikörper ist unkonjugiert
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
70
25
22
14
14
13
8
8
5
4
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Numb around the phosphorylation site of Ser276
Isotyp IgG
Spezifität Phospho-Numb (Ser276) Antibody detects endogenous levels of Numb only when phosphorylated at Ser276
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung Numb (NUMB Antibody Abstract)
Hintergrund

Description: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Gene: NUMB

Molekulargewicht 78kDa
Gen-ID 8650
UniProt P49757
Pathways Cell-Cell Junction Organization
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Numb Homolog (NUMB) (pSer276) antibody (ABIN6268078) Western blot analysis of Phospho-Numb (Ser276) in lysates of HeLa?, using Phospho-Num...