TTF1 Antikörper (Transcription Termination Factor, RNA Polymerase I) (pSer327)

Details for Product anti-TTF1 Antibody No. ABIN6268074
Target
Bindungsspezifität
pSer327
8
8
6
4
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
62
30
27
Wirt
Kaninchen
51
14
Klonalität
Polyklonal
Konjugat
Dieser TTF1 Antikörper ist unkonjugiert
4
3
3
3
3
3
3
2
2
1
1
Applikation
ELISA, Western Blotting (WB)
30
26
19
17
10
7
7
7
6
2
2
2
1
Optionen
Immunogen A synthesized peptide derived from human TTF-1 around the phosphorylation site of Ser327
Isotyp IgG
Spezifität Phospho-TTF-1 (Ser327) Antibody detects endogenous levels of TTF-1 only when phosphorylated at Ser327
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TTF-1 (TTF1 Antibody Abstract)
Hintergrund

Description: Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

Gene: NKX2-1

Molekulargewicht 42kDa
Gen-ID 7080
UniProt P43699
Pathways Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Transcription Termination Factor, RNA Polymerase I (TTF1) (pSer327) antibody (ABIN6268074) Western blot analysis of Phospho-TTF-1 (Ser327) in lysates of H441, using Phospho-TTF...