AMPA Receptor (pSer849) Antikörper

Details zu Produkt Nr. ABIN6268068
Target
Bindungsspezifität
pSer849
Reaktivität
Human, Maus, Ratte
2
1
1
Wirt
Kaninchen
2
Klonalität
Polyklonal
Applikation
ELISA, Western Blotting (WB)
2
1
Optionen
Immunogen A synthesized peptide derived from human AMPA Receptor around the phosphorylation site of GluR 1
Isotyp IgG
Spezifität Phospho-AMPA Receptor (GluR 1) (Ser849) Antibody detects endogenous levels of AMPA Receptor only when phosphorylated at GluR 1
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Hintergrund

Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene: GRIA1

Molekulargewicht 102kDa
Gen-ID 2890
UniProt P42261
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-AMPA Receptor (pSer849) antibody (ABIN6268068) Western blot analysis of Phospho-AMPA Receptor (GluR 1) (Ser849) in lysates of COLO20...