Catenin 1 (pSer320) Antikörper

Details zu Produkt Nr. ABIN6267976
Target
Bindungsspezifität
pSer320
Reaktivität
Human, Maus, Ratte
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
ELISA, Western Blotting (WB)
Optionen
Immunogen A synthesized peptide derived from human Catenin 1 around the phosphorylation site of Ser320
Isotyp IgG
Spezifität Phospho-Catenin 1 (Ser320) Antibody detects endogenous levels of Catenin 1 only when phosphorylated at Ser320
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Hintergrund

Description: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Gene: CTNND1

Molekulargewicht 105kDa
Gen-ID 1500
UniProt O60716
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Catenin 1 (pSer320) antibody (ABIN6267976) Western blot analysis of Phospho-Catenin 1 (Ser320) in lysates of HuvEc, using Phosph...