Ensa Antikörper (Endosulfine alpha) (pSer62)

Details for Product anti-ENSA Antibody No. ABIN6267970
Target
Bindungsspezifität
pSer62, pSer67
17
9
8
7
6
2
1
Reaktivität
Human, Maus, Ratte
49
13
4
1
1
1
1
1
Wirt
Kaninchen
44
4
2
Klonalität
Polyklonal
Konjugat
Dieser Ensa Antikörper ist unkonjugiert
5
4
3
3
3
2
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
34
29
18
10
6
5
3
2
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human ENSA around the phosphorylation site of Ser67
Isotyp IgG
Spezifität Phospho-ENSA (Ser67) /ARPP19 (Ser62) Antibody detects endogenous levels of ENSA only when phosphorylated at Ser67
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung ENSA (ENSA Antibody Abstract)
Hintergrund

Description: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.

Gene: ENSA

Molekulargewicht 15kDa
Gen-ID 2029
UniProt O43768
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Endosulfine alpha (ENSA) (pSer62), (pSer67) antibody (ABIN6267970) Western blot analysis of Phospho-ENSA (Ser67) /ARPP19 (Ser62) in lysates of HeLa?, us...