H2AFZ Antikörper (H2A Histone Family, Member Z) (acLys11)

Details for Product anti-H2AFZ Antibody No. ABIN6267940
Target
Bindungsspezifität
acLys11, acLys13, acLys4, acLys7
17
17
17
9
8
6
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
110
62
59
6
6
6
6
6
4
4
4
4
3
2
1
1
1
1
Wirt
Kaninchen
117
2
Klonalität
Polyklonal
Konjugat
Dieser H2AFZ Antikörper ist unkonjugiert
7
5
4
4
4
4
4
4
3
2
2
2
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
81
49
38
15
13
13
12
11
9
7
4
4
3
3
1
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Acetyl-H2A.Z ( K4/7/11/13)
Isotyp IgG
Spezifität Acetyl-H2A.Z ( K4/7/11/13) Antibody detects endogenous levels of Acetyl-H2A.Z ( K4/7/11/13)
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung Immunogen affinity purified
Target
Andere Bezeichnung H2A.Z (H2AFZ Antibody Abstract)
Hintergrund

Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Gene: H2AFZ

Molekulargewicht 14kDa
Gen-ID 3015
UniProt P0C0S5
Pathways Telomere Maintenance
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-H2A Histone Family, Member Z (H2AFZ) (acLys11), (acLys13), (acLys4), (acLys7) antibody (ABIN6267940) Western blot analysis of Acetyl-H2A.Z ( K4/7/11/13) in lysates of HeLa TSA 1M, 18 hr...