Histone H2B Type 2-E (pTyr43) Antikörper

Details zu Produkt Nr. ABIN6267926
Target
Bindungsspezifität
pTyr43
15
8
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
40
13
13
Wirt
Kaninchen
36
4
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
30
28
7
4
4
3
3
2
2
1
Optionen
Immunogen A synthesized peptide derived from human H2B around the phosphorylation site of Y43
Isotyp IgG
Spezifität Phospho-H2B (Y43) Antibody Antibody detects endogenous levels of H2B only when phosphorylated at Y43
Kreuzreaktivität Human
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung H2B
Hintergrund

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: H2BFS

Molekulargewicht 14kDa
Gen-ID 102724334
UniProt P57053
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Histone H2B Type 2-E (pTyr43) antibody (ABIN6267926) Western blot analysis of Phospho-H2B (Y43) in lysates of HL-60 etoposide-treated 50 ...