Histone H4 (pSer88) Antikörper

Details zu Produkt Nr. ABIN6267924
Target
Bindungsspezifität
pSer88
48
45
42
31
24
22
20
18
18
17
16
15
15
15
12
11
11
10
10
10
10
10
9
8
6
5
5
4
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Human, Maus, Schwein, Ratte
491
400
373
42
40
22
20
18
17
16
14
10
9
8
6
6
5
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
483
30
3
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
28
26
25
25
25
25
25
7
7
5
5
5
5
5
2
2
2
Applikation
ELISA, Western Blotting (WB)
315
155
152
104
70
66
63
61
48
38
34
23
20
9
7
6
5
4
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Histone H4 around the phosphorylation site of Ser88
Isotyp IgG
Spezifität Phospho-Histone H4(Ser88) Antibody detects endogenous levels of Histone H4 only when phosphorylated at Ser88
Kreuzreaktivität Rind (Kuh), Human, Maus, Schwein, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Hintergrund

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4

Molekulargewicht 11kDa
Gen-ID 121, 504, 554
UniProt P62805
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Histone H4 (pSer88) antibody (ABIN6267924) Western blot analysis of Phospho-Histone H4(Ser88) in lysates of A431, using Phospho-...