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Histone H4 (pSer88) Antikörper Primary Antibody

Reaktivität: Rind (Kuh), Human, Maus, Schwein, Ratte ELISA, WB Wirt: Kaninchen Polyclonal
Produktnummer ABIN6267924
$450.00
Zzgl. Versandkosten $45.00
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen
  • Target
    Bindungsspezifität
    pSer88
    Reaktivität
    Rind (Kuh), Human, Maus, Schwein, Ratte
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Konjugat
    Unkonjugiert
    Applikation
    ELISA, Western Blotting (WB)
    Spezifität
    Phospho-Histone H4(Ser88) Antibody detects endogenous levels of Histone H4 only when phosphorylated at Ser88
    Kreuzreaktivität
    Rind (Kuh), Human, Maus, Schwein, Ratte (Rattus)
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human Histone H4 around the phosphorylation site of Ser88
    Isotyp
    IgG
  • Target
    Hintergrund

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4

    Molekulargewicht
    11kDa
    Gen-ID
    121, 504, 554
    UniProt
    P62805
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
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