Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (pThr29) Antikörper

Details zu Produkt Nr. ABIN6267908
Target
Bindungsspezifität
pThr29
27
20
17
16
13
13
11
8
8
8
7
6
6
5
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
205
96
76
4
4
2
2
1
1
1
Wirt
Kaninchen
180
23
7
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
16
15
12
11
11
11
4
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
105
90
65
41
24
21
20
17
8
6
5
3
1
1
1
Optionen
Immunogen A synthesized peptide derived from human LC3B around the phosphorylation site of Thr29
Isotyp IgG
Spezifität Phospho-LC3B(Thr29) Antibody detects endogenous levels of LC3B only when phosphorylated at Thr29
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung LC3B (MAP1LC3B Antibody Abstract)
Hintergrund

Description: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Gene: MAP1LC3B

Molekulargewicht 14kDa, 16kDa
Gen-ID 81631
UniProt Q9GZQ8
Pathways Autophagie
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (pThr29) antibody (ABIN6267908) Western blot analysis of Phospho-LC3B(Thr29) in lysates of hela overnight chloroqui...