CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (pTyr207) Antikörper

Details zu Produkt Nr. ABIN6267906
Target
Bindungsspezifität
pTyr207
22
10
9
9
7
7
7
4
3
3
2
2
2
2
1
1
1
1
Reaktivität
Human, Maus, Ratte
120
70
25
9
9
2
2
Wirt
Kaninchen
63
50
27
15
5
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
20
18
15
8
3
2
2
2
2
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
96
92
52
49
45
21
13
10
9
7
6
5
4
2
2
1
Optionen
Immunogen A synthesized peptide derived from human CD79B around the phosphorylation site of Tyr207
Isotyp IgG
Spezifität Phospho-CD79B(Tyr207) Antibody detects endogenous levels of CD79B only when phosphorylated at Tyr207
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung CD79B (CD79B Antibody Abstract)
Hintergrund

Description: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Gene: CD79B

Molekulargewicht 14kDa, 30-50kDa
Gen-ID 974
UniProt P40259
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (pTyr207) antibody (ABIN6267906) Western blot analysis of Phospho-CD79B(Tyr207) in lysates of Raji?, using Phospho-CD7...