TAB2 Antikörper (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2) (pSer450)

Details for Product anti-TAB2 Antibody No. ABIN6267878
Target
Bindungsspezifität
pSer450
4
3
3
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus
26
9
9
6
4
3
3
3
3
1
1
1
1
Wirt
Kaninchen
19
5
3
Klonalität
Polyklonal
Applikation
ELISA, Western Blotting (WB)
18
8
7
7
5
3
3
2
1
Optionen
Immunogen A synthesized peptide derived from human TAB2 around the phosphorylation site of Ser450
Isotyp IgG
Spezifität Phospho-TAB2(Ser450) Antibody detects endogenous levels of TAB2 only when phosphorylated at Ser450
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TAB2 (TAB2 Antibody Abstract)
Hintergrund

Description: Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.

Gene: TAB2

Molekulargewicht 80-84kDa
Gen-ID 23118
UniProt Q9NYJ8
Pathways T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (pSer450) antibody (ABIN6267878) Western blot analysis of Phospho-TAB2(Ser450) in lysates of 293T hIL-1 50 ng/ml, usi...