APAF1 Antikörper (Apoptotic Peptidase Activating Factor 1) (pSer320)

Details for Product anti-APAF1 Antibody No. ABIN6267874
Target
Bindungsspezifität
pSer320
25
23
15
15
5
5
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
120
81
60
5
3
2
2
1
1
Wirt
Kaninchen
103
13
11
2
Klonalität
Polyklonal
Konjugat
Dieser APAF1 Antikörper ist unkonjugiert
6
5
4
4
4
4
4
3
3
2
2
2
2
2
2
2
Applikation
ELISA, Western Blotting (WB)
83
41
37
29
26
24
19
13
9
4
4
3
1
1
1
Optionen
Immunogen A synthesized peptide derived from human APAF around the phosphorylation site of Ser320
Isotyp IgG
Spezifität Phospho-APAF(Ser320) Antibody detects endogenous levels of APAF only when phosphorylated at Ser320
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung APAF (APAF1 Antibody Abstract)
Hintergrund

Description: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Gene: APAF1

Molekulargewicht 139kDa
Gen-ID 317
UniProt O14727
Pathways p53 Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Tube Formation, Positive Regulation of Endopeptidase Activity
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (pSer320) antibody (ABIN6267874) Western blot analysis of Phospho-APAF(Ser320) in lysates of Human heart tissue, using...