Peroxisome Proliferator-Activated Receptor delta (PPARD) (pThr256) Antikörper

Details zu Produkt Nr. ABIN6267870
Target
Bindungsspezifität
pThr256
26
9
9
8
7
5
5
4
3
3
3
3
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Schwein, Ratte
102
50
34
8
7
6
6
6
5
3
1
1
1
1
1
Wirt
Kaninchen
88
20
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
13
6
5
5
5
5
3
3
3
2
2
2
Applikation
ELISA, Western Blotting (WB)
97
65
23
18
8
7
6
5
4
3
3
3
2
2
Optionen
Immunogen A synthesized peptide derived from human PPARD around the phosphorylation site of Thr256
Isotyp IgG
Spezifität Phospho-PPARD (Thr256) Antibody detects endogenous levels of PPARD only when phosphorylated at Thr256
Kreuzreaktivität Human, Maus, Schwein, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung PPARD (PPARD Antibody Abstract)
Hintergrund

Description: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.

Gene: PPARD

Molekulargewicht 50kDa
Gen-ID 5467
UniProt Q03181
Pathways Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (pThr256) antibody (ABIN6267870) Western blot analysis of Phospho-PPARD (Thr256) in lysates of 3T3?, using Phospho-PPA...