P2RX7 Antikörper (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7) (pSer390)

Details for Product anti-P2RX7 Antibody No. ABIN6267860
Target
Bindungsspezifität
pSer390
16
12
9
7
3
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
73
45
28
3
3
3
2
2
1
1
Wirt
Kaninchen
64
8
6
3
Klonalität
Polyklonal
Konjugat
Dieser P2RX7 Antikörper ist unkonjugiert
7
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
56
38
31
13
11
10
7
6
1
1
Optionen
Immunogen A synthesized peptide derived from human P2X7 around the phosphorylation site of Ser390
Isotyp IgG
Spezifität Phospho-P2X7(Ser390) Antibody detects endogenous levels of P2X7 only when phosphorylated at Ser390
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung P2X7 (P2RX7 Antibody Abstract)
Hintergrund

Description: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells (PubMed:21821797, PubMed:23303206).

Gene: P2RX7

Molekulargewicht 78kDa
Gen-ID 5027
UniProt Q99572
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (pSer390) antibody (ABIN6267860) Western blot analysis of Phospho-P2X7(Ser390) in lysates of Jurkat?, using Phospho-P2...