SOS1 Antikörper (Son of Sevenless Homolog 1 (Drosophila)) (pSer1082)

Details for Product anti-SOS1 Antibody No. ABIN6267850
Target
Bindungsspezifität
pSer1082
3
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
21
10
5
5
4
4
3
3
3
2
2
1
1
Wirt
Kaninchen
14
8
2
Klonalität
Polyklonal
Applikation
ELISA, Western Blotting (WB)
18
14
6
2
1
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human SOS1 around the phosphorylation site of Ser1082
Isotyp IgG
Spezifität Phospho-SOS1(Ser1082) Antibody detects endogenous levels of SOS1 only when phosphorylated at Ser1082
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung SOS1 (SOS1 Antibody Abstract)
Hintergrund

Description: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

Gene: SOS1

Molekulargewicht 152kDa
Gen-ID 6654
UniProt Q07889
Pathways RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Son of Sevenless Homolog 1 (Drosophila) (SOS1) (pSer1082) antibody (ABIN6267850) Western blot analysis of Phospho-SOS1(Ser1082) in lysates of Raji?, using Phospho-SOS...