Tumor Protein P53 Binding Protein 2 (TP53BP2) (pSer698) Antikörper

Details zu Produkt Nr. ABIN6267846
Target
Bindungsspezifität
pSer698
13
10
8
3
3
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
61
23
20
6
4
3
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
58
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
40
24
13
7
6
3
2
2
2
1
1
Optionen
Immunogen A synthesized peptide derived from human ASPP2 around the phosphorylation site of Ser698
Isotyp IgG
Spezifität Phospho-ASPP2 (Ser698) Antibody detects endogenous levels of ASPP2 only when phosphorylated at Ser698
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung ASPP2 (TP53BP2 Antibody Abstract)
Hintergrund

Description: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Gene: TP53BP2

Molekulargewicht 126kDa
Gen-ID 7159
UniProt Q13625
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Tumor Protein P53 Binding Protein 2 (TP53BP2) (pSer698) antibody (ABIN6267846) Western blot analysis of Phospho-ASPP2 (Ser698) in lysates of Jurkat?, using Phospho-...