SIN3A Antikörper (SIN3 Transcription Regulator Homolog A (Yeast)) (pSer832)

Details for Product anti-SIN3A Antibody No. ABIN6267832
Target
Bindungsspezifität
pSer832
8
8
7
5
4
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
44
41
26
4
4
3
2
2
2
2
2
2
1
1
1
Wirt
Kaninchen
52
3
2
Klonalität
Polyklonal
Konjugat
Dieser SIN3A Antikörper ist unkonjugiert
5
3
3
2
2
2
2
2
2
2
2
2
Applikation
ELISA, Western Blotting (WB)
42
26
11
8
7
6
6
5
3
3
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human SIN3A around the phosphorylation site of Ser832
Isotyp IgG
Spezifität Phospho-SIN3A(Ser832) Antibody detects endogenous levels of SIN3A only when phosphorylated at Ser832
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung SIN3A (SIN3A Antibody Abstract)
Hintergrund

Description: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).

Gene: SIN3A

Molekulargewicht 145kDa
Gen-ID 25942
UniProt Q96ST3
Pathways Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) (pSer832) antibody (ABIN6267832) Western blot analysis of Phospho-SIN3A(Ser832) in lysates of MCF7, using Phospho-SIN3...