MPRIP Antikörper (Myosin Phosphatase rho Interacting Protein) (pThr542)

Details for Product anti-MPRIP Antibody No. ABIN6267824
Target
Bindungsspezifität
pThr542
31
13
10
8
8
7
7
7
3
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
83
78
37
4
4
2
2
1
1
Wirt
Kaninchen
102
2
Klonalität
Polyklonal
Konjugat
Dieser MPRIP Antikörper ist unkonjugiert
9
5
5
5
5
5
5
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
75
63
37
27
24
5
4
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human RIP3 around the phosphorylation site of Thr542
Isotyp IgG
Spezifität Phospho-RIP3(Thr542) Antibody detects endogenous levels of RIP3 only when phosphorylated at Thr542
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung RIP3 (MPRIP Antibody Abstract)
Hintergrund

Description: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Gene: MPRIP

Molekulargewicht 115kDa
Gen-ID 23164
UniProt Q6WCQ1
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Myosin Phosphatase rho Interacting Protein (MPRIP) (pThr542) antibody (ABIN6267824) Western blot analysis of Phospho-RIP3(Thr542) in lysates of L-929, using Phospho-RIP3...