TWIST2 Antikörper (Twist Homolog 2 (Drosophila)) (AA 26-30)

Details for Product anti-TWIST2 Antibody No. ABIN6267794
Target
Bindungsspezifität
AA 26-30
6
4
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
39
21
20
Wirt
Kaninchen
26
13
Klonalität
Polyklonal
Konjugat
Dieser TWIST2 Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
25
15
13
9
8
3
2
2
1
1
1
Optionen
Immunogen Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.
Isotyp IgG
Spezifität The antibody detects endogenous level of total Twist2 protein.
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung Twist2 (TWIST2 Antibody Abstract)
Hintergrund

Description: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Gene: TWIST2

Molekulargewicht 18kDa
Gen-ID 117581
UniProt Q8WVJ9
Pathways Chromatin Binding
Applikations-hinweise WB 1:500-1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Bilder
Image no. 1 for anti-Twist Homolog 2 (Drosophila) (TWIST2) (AA 26-30) antibody (ABIN6267794) Western blot analysis of extracts from A549, Hela and 3T3 cells using Twist2 Antibody
Image no. 2 for anti-Twist Homolog 2 (Drosophila) (TWIST2) (AA 26-30) antibody (ABIN6267794) ABIN6267795 at 1/100 staining human liver tissue sections by IHC-P. The tissue was fo...