Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 289-293) Antikörper

Details zu Produkt Nr. ABIN6267760
Target
Bindungsspezifität
AA 289-293
21
16
16
15
8
8
7
4
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
115
66
41
2
1
1
1
Wirt
Kaninchen
101
7
6
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
11
7
7
5
5
5
5
5
5
4
4
4
1
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
83
61
36
24
13
10
4
3
3
1
1
1
1
Optionen
Immunogen Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Isotyp IgG
Spezifität The antibody detects endogenous level of total WASP protein.
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung WASP (WAS Antibody Abstract)
Hintergrund

Description: Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.

Gene: WAS

Molekulargewicht 53kDa
Gen-ID 7454
UniProt P42768
Applikations-hinweise WB 1:500-1:1000, IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Bilder
Image no. 1 for anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 289-293) antibody (ABIN6267760) Western blot analysis of extract from Hela, JK and Raji cells using WASP Antibody
Image no. 2 for anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 289-293) antibody (ABIN6267760) ABIN6267761 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilize...