Nuclear Receptor Coactivator 3 (NCOA3) Antikörper

Details zu Produkt Nr. ABIN6267744
Target
Reaktivität
Human, Maus
86
19
7
5
4
3
3
2
2
1
1
1
Wirt
Kaninchen
70
17
2
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
59
31
17
14
13
5
5
3
3
3
2
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human NCoA3
Isotyp IgG
Spezifität NCoA3 Antibody detects endogenous levels of total NCoA3 protein
Kreuzreaktivität Human, Maus
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung NCoA3 (NCOA3 Antibody Abstract)
Hintergrund

Description: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.

Gene: NCOA3

Molekulargewicht 155kDa
Gen-ID 8202
UniProt Q9Y6Q9
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
Applikations-hinweise WB 1:1000-3000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Nuclear Receptor Coactivator 3 (NCOA3) antibody (ABIN6267744) Western blot analysis NCoA3 using NIH-3T3 whole cell lysates