VPS33B Antikörper

Produktnummer ABIN6265997

Produktdetails anti-VPS33B Antikörper

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS33B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: VPS33B antibody detects endogenous levels of VPS33B.

Kreuzreaktivität: Human, Maus, Ratte (Rattus), Zebrafisch (Danio rerio)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human VPS33B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Andere Bezeichnung: VPS33B (VPS33B Produkte)

Synonyme: CG5127 antikoerper, Dmel\\CG5127 antikoerper, VPS33b antikoerper, Vps 33B antikoerper, dVps33B antikoerper, VPS33B antikoerper, GB11157 antikoerper, zgc:110803 antikoerper, Vacuolar protein sorting 33B antikoerper, VPS33B, late endosome and lysosome associated antikoerper, vacuolar protein sorting-associated protein 33B antikoerper, vacuolar protein sorting 33B antikoerper, Vps33B antikoerper, VPS33B antikoerper, LOC551135 antikoerper, Vps33b antikoerper, vps33b antikoerper

Hintergrund:

Description: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity).

Gene: VPS33B

Molekulargewicht: 71 kDa

Gen-ID: 26276

UniProt: Q9H267