USP16 Antikörper (N-Term)

Produktnummer ABIN6265912

Produktdetails anti-USP16 Antikörper

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: USP16 Antibody detects endogenous levels of total USP16.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human USP16, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu USP16

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Andere Bezeichnung: USP16 (USP16 Produkte)

Synonyme: ubp-m antikoerper, USP16 antikoerper, UBP-M antikoerper, 1200004E02Rik antikoerper, 2810483I07Rik antikoerper, 6330514E22Rik antikoerper, UBPM antikoerper, si:ch211-238e22.5 antikoerper, si:dkey-121n8.2 antikoerper, wu:fc76b02 antikoerper, wu:fc76b08 antikoerper, universal stress protein antikoerper, ubiquitin specific peptidase 16 antikoerper, ubiquitin specific peptidase 16 L homeolog antikoerper, usp16 antikoerper, USP16 antikoerper, Usp16 antikoerper, usp16.L antikoerper

Hintergrund:

Description: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

Gene: USP16

Molekulargewicht: 94 kDa

Gen-ID: 10600

UniProt: Q9Y5T5