USP14 Antikörper (Internal Region)

Produktnummer ABIN6265911

Produktdetails anti-USP14 Antikörper

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: USP14 Antibody detects endogenous levels of total USP14.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human USP14, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Andere Bezeichnung: USP14 (USP14 Produkte)

Synonyme: TGT antikoerper, DDBDRAFT_0202821 antikoerper, DDBDRAFT_0237695 antikoerper, DDB_0202821 antikoerper, DDB_0237695 antikoerper, 2610005K12Rik antikoerper, 2610037B11Rik antikoerper, AW107924 antikoerper, C78769 antikoerper, ax antikoerper, zgc:55949 antikoerper, wu:fk63d09 antikoerper, MGC81945 antikoerper, tgt antikoerper, MGC69343 antikoerper, USP14 antikoerper, ubiquitin specific peptidase 14 antikoerper, peptidase C19 family protein antikoerper, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) antikoerper, ubiquitin specific protease 14 antikoerper, ubiquitin specific peptidase 14 S homeolog antikoerper, universal stress protein antikoerper, Ubiquitin carboxyl-terminal hydrolase 14 antikoerper, USP14 antikoerper, usp14 antikoerper, Usp14 antikoerper, Bm1_28765 antikoerper, usp14.S antikoerper, RR_RS06480 antikoerper, usp-14 antikoerper

Hintergrund:

Description: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.

Gene: USP14

Molekulargewicht: 56 kDa

Gen-ID: 9097

UniProt: P54578