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UBE2D1 Antikörper (C-Term)

UBE2D1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265844
  • Target Alle UBE2D1 Antikörper anzeigen
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 51
    • 20
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 48
    • 3
    Kaninchen
    Klonalität
    • 47
    • 4
    Polyklonal
    Konjugat
    • 16
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2D1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 21
    • 15
    • 13
    • 13
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    UBE2D1 Antibody detects endogenous levels of total UBE2D1.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human UBE2D1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product UBE2D1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    Andere Bezeichnung
    UBE2D1 (UBE2D1 Produkte)
    Synonyme
    E2(17)KB1 antikoerper, SFT antikoerper, UBC4/5 antikoerper, UBCH5 antikoerper, UBCH5A antikoerper, ube2d1 antikoerper, wu:fc16h06 antikoerper, zgc:73096 antikoerper, e2(17)kb1 antikoerper, sft antikoerper, ubc4/5 antikoerper, ubch5 antikoerper, ubch5a antikoerper, ubiquitin conjugating enzyme E2 D1 antikoerper, ubiquitin-conjugating enzyme E2D 1 antikoerper, ubiquitin-conjugating enzyme E2D 1b antikoerper, ubiquitin conjugating enzyme E2 D1 S homeolog antikoerper, UBE2D1 antikoerper, Ube2d1 antikoerper, ube2d1b antikoerper, ube2d1.S antikoerper, ube2d1 antikoerper
    Hintergrund

    Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148).

    Gene: UBE2D1

    Molekulargewicht
    17kDa
    Gen-ID
    7321
    UniProt
    P51668
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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