Tuberin Antikörper (Internal Region)
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- Target Alle Tuberin (TSC2) Antikörper anzeigen
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Tuberin Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Tuberin/TSC2 Antibody detects endogenous levels of total Tuberin/TSC2.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Tuberin/TSC2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TSC2 Primärantikörper
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anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 Reaktivität: Human DB, IF Wirt: Kaninchen Polyclonal RB11388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyTSC2 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (Ser1798) antibodyTSC2 Reaktivität: Human ELISA, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
- Andere Bezeichnung
- TSC2 (TSC2 Produkte)
- Synonyme
- TSC2 antikoerper, fc16b02 antikoerper, tuberin antikoerper, wu:fc16b02 antikoerper, LAM antikoerper, TSC4 antikoerper, Nafld antikoerper, Tcs2 antikoerper, Rc antikoerper, TSC complex subunit 2 antikoerper, tuberin antikoerper, hypothetical protein antikoerper, tuberous sclerosis 2 antikoerper, TSC2 antikoerper, LOC5569538 antikoerper, tsc2 antikoerper, PGTG_00159 antikoerper, Tsc2 antikoerper
- Hintergrund
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Description: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, PubMed:28215400). Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1 (PubMed:15340059). May also play a role in microtubule-mediated protein transport (By similarity). Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 (By similarity).
Gene: TSC2
- Molekulargewicht
- 200kDa
- Gen-ID
- 7249
- UniProt
- P49815
- Pathways
- RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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