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TNFRSF10B Antikörper (N-Term)

Name: TNFRSF10B Antikörper (N-Term)
SKU: ABIN6265635
Price: 698.46 EUR
Availability: InStock

TNFRSF10B Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of HL-60 lysate using TNFRSF10B antibody.

ABIN6276636 at 1/100 staining Human prostate tissue by IHC-P.

IHC

2 Abbildungen

(1 reference)

Produktnummer ABIN6265635

Datenblatt (PDF)

Target Alle TNFRSF10B Antikörper anzeigen

TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Bindungsspezifität
15

7

6

5

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
98

20

4

1

1
Human
Wirt
62

40

3

2

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
60

47

2
Polyklonal
Konjugat
71

11

6

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser TNFRSF10B Antikörper ist unkonjugiert
Applikation
73

37

30

24

17

16

15

13

12

11

8

5

4

3

3

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität

DR5 Antibody detects endogenous levels of total DR5.

Aufreinigung

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human DR5, corresponding to a region within N-terminal amino acids.

Isotyp

IgG

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TNFRSF10B Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibody
TNFRSF10B Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) antibody
TNFRSF10B Reaktivität: Human WB, FACS, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 2H5B8 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 1-440) antibody
TNFRSF10B Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 266-393) antibody
TNFRSF10B Reaktivität: Human IHC, StM Wirt: Maus Monoclonal DR5-3381 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 71-170) antibody
TNFRSF10B Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 2D6 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 301-381) antibody
TNFRSF10B Reaktivität: Human WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibody
TNFRSF10B Reaktivität: Human, Maus WB, ICC Wirt: Maus Monoclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Extracellular Domain) antibody (APC)
TNFRSF10B Reaktivität: Human FACS Wirt: Maus Monoclonal DR5-01-1 APC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-186) antibody
TNFRSF10B Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM113 unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Luo, Pan, Liu, Yuan, Yan: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
Target

TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Andere Bezeichnung

TNFRSF10B (TNFRSF10B Produkte)

Synonyme

TNFRSF10B antikoerper, dr5 antikoerper, cd262 antikoerper, killer antikoerper, trick2 antikoerper, trickb antikoerper, xDR-M1 antikoerper, xDR-M2 antikoerper, ztnfr9 antikoerper, trailr2 antikoerper, trick2a antikoerper, trick2b antikoerper, CD262 antikoerper, DR5 antikoerper, KILLER antikoerper, KILLER/DR5 antikoerper, TRAIL-R2 antikoerper, TRAILR2 antikoerper, TRICK2 antikoerper, TRICK2A antikoerper, TRICK2B antikoerper, TRICKB antikoerper, ZTNFR9 antikoerper, Ly98 antikoerper, MK antikoerper, tumor necrosis factor receptor superfamily, member 10b antikoerper, tumor necrosis factor receptor superfamily member 10b S homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b L homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b antikoerper, TNF receptor superfamily member 10b antikoerper, Tnfrsf10b antikoerper, TNFRSF10B antikoerper, tnfrsf10b.S antikoerper, tnfrsf10b.L antikoerper, tnfrsf10b antikoerper

Hintergrund

Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Gene: TNFRSF10B

Molekulargewicht

48kDa

Gen-ID

8795

UniProt

O14763

Pathways

p53 Signalweg, Apoptose, Positive Regulation of Endopeptidase Activity