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TLR9 Antikörper (Internal Region)

TLR9 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265605
  • Target Alle TLR9 Antikörper anzeigen
    TLR9 (Toll-Like Receptor 9 (TLR9))
    Bindungsspezifität
    • 19
    • 15
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 94
    • 39
    • 13
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 64
    • 33
    • 7
    • 4
    • 1
    Kaninchen
    Klonalität
    • 72
    • 37
    Polyklonal
    Konjugat
    • 62
    • 13
    • 12
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR9 Antikörper ist unkonjugiert
    Applikation
    • 77
    • 49
    • 45
    • 45
    • 23
    • 15
    • 12
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    TLR9 Antibody detects endogenous levels of total TLR9.
    Homologie
    Horse,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TLR9, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product TLR9 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TLR9 (Toll-Like Receptor 9 (TLR9))
    Andere Bezeichnung
    TLR9 (TLR9 Produkte)
    Synonyme
    CD289 antikoerper, toll like receptor 9 antikoerper, toll-like receptor 9 antikoerper, TLR9 antikoerper, Tlr9 antikoerper
    Hintergrund

    Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:11564765, PubMed:17932028). Controls lymphocyte response to Helicobacter infection (By similarity). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed:23857366).

    Gene: TLR9

    Molekulargewicht
    117kDa
    Gen-ID
    54106
    UniProt
    Q9NR96
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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