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TLR1 Antikörper (Internal Region)

TLR1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265596
  • Target Alle TLR1 Antikörper anzeigen
    TLR1 (Toll-Like Receptor 1 (TLR1))
    Bindungsspezifität
    • 16
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 74
    • 49
    • 29
    • 4
    • 4
    • 1
    Human, Maus, Ratte
    Wirt
    • 73
    • 15
    • 2
    Kaninchen
    Klonalität
    • 76
    • 14
    Polyklonal
    Konjugat
    • 37
    • 14
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR1 Antikörper ist unkonjugiert
    Applikation
    • 69
    • 37
    • 32
    • 29
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    TLR1 Antibody detects endogenous levels of total TLR1.
    Homologie
    Bovine,Horse,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TLR1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product TLR1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TLR1 (Toll-Like Receptor 1 (TLR1))
    Andere Bezeichnung
    TLR1 (TLR1 Produkte)
    Synonyme
    CD281 antikoerper, TIL antikoerper, TIL. LPRS5 antikoerper, rsc786 antikoerper, toll like receptor 1 antikoerper, toll-like receptor 1 antikoerper, TLR1 antikoerper, Tlr1 antikoerper
    Hintergrund

    Description: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

    Gene: TLR1

    Molekulargewicht
    90kDa
    Gen-ID
    7096
    UniProt
    Q15399
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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