SLC22A17 Antikörper (C-Term)
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- Target Alle SLC22A17 Antikörper anzeigen
- SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC22A17 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- SLC22A17 Antibody detects endogenous levels of total SLC22A17.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SLC22A17, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SLC22A17 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
- Andere Bezeichnung
- SLC22A17 (SLC22A17 Produkte)
- Synonyme
- 1700094C23Rik antikoerper, 24p3R antikoerper, AU041908 antikoerper, AW555662 antikoerper, BOIT antikoerper, Boct antikoerper, mBOCT antikoerper, BOCT antikoerper, NGALR antikoerper, NGALR2 antikoerper, NGALR3 antikoerper, hBOIT antikoerper, rBOCT antikoerper, solute carrier family 22 member 17 antikoerper, solute carrier family 22 (organic cation transporter), member 17 antikoerper, solute carrier family 22, member 17 antikoerper, SLC22A17 antikoerper, Slc22a17 antikoerper
- Hintergrund
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Description: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).
Gene: SLC22A17
- Molekulargewicht
- 58 kDa
- Gen-ID
- 51310
- UniProt
- Q8WUG5
- Pathways
- Transition Metal Ion Homeostasis
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