SFRP1 Antikörper (Internal Region)
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- Target Alle SFRP1 Antikörper anzeigen
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SFRP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- SFRP1 Antibody detects endogenous levels of total SFRP1.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SFRP1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SFRP1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
- Andere Bezeichnung
- SFRP1 (SFRP1 Produkte)
- Synonyme
- FRP antikoerper, FRP-1 antikoerper, FRP1 antikoerper, FrzA antikoerper, SARP2 antikoerper, 2210415K03Rik antikoerper, AW011917 antikoerper, AW107218 antikoerper, AW742929 antikoerper, sFRP-1 antikoerper, CSFRP1 antikoerper, SFRP1 antikoerper, XfrzA antikoerper, frp antikoerper, frp-1 antikoerper, frp1 antikoerper, frzA antikoerper, sarp2 antikoerper, sfrp1 antikoerper, LOC100231868 antikoerper, Srfp1a antikoerper, wu:fd19b09 antikoerper, secreted frizzled related protein 1 antikoerper, secreted frizzled-related protein 1 antikoerper, Secreted frizzled-related protein 1 antikoerper, secreted frizzled-related protein 1a antikoerper, secreted frizzled-related protein 1b antikoerper, SFRP1 antikoerper, Sfrp1 antikoerper, sfrp1 antikoerper, sfrp1a antikoerper, sfrp1b antikoerper
- Hintergrund
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Description: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Gene: SFRP1
- Molekulargewicht
- 35 kDa
- Gen-ID
- 6422
- UniProt
- Q8N474
- Pathways
- WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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