SCNN1A Antikörper (Internal Region)

Produktnummer ABIN6264945

Produktdetails anti-SCNN1A Antikörper

Target: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Bindungsspezifität: Internal Region

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCNN1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA

Spezifität: SCNN1A Antibody detects endogenous levels of total SCNN1A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SCNN1A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:100-200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-SCNN1A Antikörper (ABIN6264945)

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Details zu SCNN1A

Target: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Andere Bezeichnung: SCNN1A (SCNN1A Produkte)

Synonyme: BESC2 antikoerper, ENaCa antikoerper, ENaCalpha antikoerper, SCNEA antikoerper, SCNN1 antikoerper, ENaC antikoerper, Scnn1 antikoerper, mENaC antikoerper, SCNN1A antikoerper, alphaxENaC antikoerper, besc2 antikoerper, enaca antikoerper, scnn1 antikoerper, ENAC antikoerper, sodium channel epithelial 1 alpha subunit antikoerper, sodium channel, nonvoltage-gated 1 alpha antikoerper, sodium channel, non voltage gated 1 alpha subunit L homeolog antikoerper, Scnn1a antikoerper, SCNN1A antikoerper, scnn1a.L antikoerper

Hintergrund:

Description: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception.

Gene: SCNN1A

Molekulargewicht: 76kDa

Gen-ID: 6337

UniProt: P37088