POLR3K Antikörper (Internal Region)

Produktnummer ABIN6264820

Produktdetails anti-POLR3K Antikörper

Target: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR3K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: RPC10 Antibody detects endogenous levels of total RPC10.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RPC10, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu POLR3K

Target: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Andere Bezeichnung: POLR3K (POLR3K Produkte)

Synonyme: MGC108467 antikoerper, POLR3K antikoerper, 12.3kDa antikoerper, 1500004O14Rik antikoerper, AI196849 antikoerper, AU014893 antikoerper, C11 antikoerper, RPC10 antikoerper, RPC11 antikoerper, C11-RNP3 antikoerper, RPC12.5 antikoerper, hRPC11 antikoerper, RNA polymerase III subunit K antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antikoerper, polymerase (RNA) III (DNA directed) polypeptide K antikoerper, Polr3k antikoerper, polr3k.S antikoerper, polr3k antikoerper, POLR3K antikoerper

Hintergrund:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Gene: POLR3K

Molekulargewicht: 12 kDa

Gen-ID: 51728

UniProt: Q9Y2Y1