POLR2G Antikörper (Internal Region)

Produktnummer ABIN6264819

Produktdetails anti-POLR2G Antikörper

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: RPB7 Antibody detects endogenous levels of total RPB7.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RPB7, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu POLR2G

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Andere Bezeichnung: POLR2G (POLR2G Produkte)

Synonyme: RPB19 antikoerper, RPB7 antikoerper, hRPB19 antikoerper, hsRPB7 antikoerper, Rpb7 antikoerper, POLR2G antikoerper, 2410046K11Rik antikoerper, A230108L04Rik antikoerper, C76415 antikoerper, RBP7 antikoerper, Rpo2-7l antikoerper, RNA polymerase II subunit G antikoerper, polymerase (RNA) II (DNA directed) polypeptide G antikoerper, polymerase (RNA) II (DNA directed) polypeptide G L homeolog antikoerper, POLR2G antikoerper, Polr2g antikoerper, polr2g antikoerper, polr2g.L antikoerper

Hintergrund:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

Gene: POLR2G

Molekulargewicht: 19 kDa

Gen-ID: 5436

UniProt: P62487

Pathways: Regulatorische RNA Pathways