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RNF6 Antikörper (Internal Region)

RNF6 Reaktivität: Human WB, ELISA, IF, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264791
  • Target Alle RNF6 Antikörper anzeigen
    RNF6 (RING Finger Protein 6 (RNF6))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 50
    • 19
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 6
    Kaninchen
    Klonalität
    • 49
    • 3
    Polyklonal
    Konjugat
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF6 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 22
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Spezifität
    RNF6 Antibody detects endogenous levels of total RNF6.
    Homologie
    Horse
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RNF6, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product RNF6 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    RNF6 (RING Finger Protein 6 (RNF6))
    Andere Bezeichnung
    RNF6 (RNF6 Produkte)
    Synonyme
    1200013I08Rik antikoerper, 5730419H05Rik antikoerper, AA537053 antikoerper, ring finger protein 6 antikoerper, ring finger protein (C3H2C3 type) 6 antikoerper, RNF6 antikoerper, Rnf6 antikoerper
    Hintergrund

    Description: E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.

    Gene: RNF6

    Molekulargewicht
    78kDa
    Gen-ID
    6049
    UniProt
    Q9Y252
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
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