PTGES3 Antikörper (C-Term)

Produktnummer ABIN6264507

Produktdetails anti-PTGES3 Antikörper

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGES3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: P23 Antibody detects endogenous levels of total p23.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human p23, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PTGES3

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Andere Bezeichnung: PTGES3 (PTGES3 Produkte)

Synonyme: P23 antikoerper, TEBP antikoerper, cPGES antikoerper, PTGES3 antikoerper, 5730442A20Rik antikoerper, Ptges antikoerper, Tebp antikoerper, p23 antikoerper, sid3177 antikoerper, RGD1561913 antikoerper, CPGES antikoerper, cPGES-1 antikoerper, ptges3 antikoerper, wu:fb98d06 antikoerper, zgc:65804 antikoerper, zgc:77131 antikoerper, tebp antikoerper, wu:fb50a04 antikoerper, zgc:86751 antikoerper, prostaglandin E synthase 3 antikoerper, prostaglandin E synthase 3 (cytosolic) pseudogene antikoerper, prostaglandin E synthase 3a (cytosolic) antikoerper, prostaglandin E synthase 3 L homeolog antikoerper, prostaglandin E synthase 3b (cytosolic) antikoerper, PTGES3 antikoerper, LOC743066 antikoerper, Ptges3 antikoerper, ptges3a antikoerper, ptges3.L antikoerper, ptges3b antikoerper

Hintergrund:

Description: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).

Gene: PTGES3

Molekulargewicht: 19kDa

Gen-ID: 10728

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process