PSMC4 Antikörper (C-Term)

Produktnummer ABIN6264481

Produktdetails anti-PSMC4 Antikörper

Target: PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: PSMC4 Antibody detects endogenous levels of total PSMC4.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSMC4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PSMC4

Target: PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))

Andere Bezeichnung: PSMC4 (PSMC4 Produkte)

Synonyme: NCU02260.1 antikoerper, AO090003000692 antikoerper, DDBDRAFT_0188209 antikoerper, DDBDRAFT_0191435 antikoerper, DDB_0188209 antikoerper, DDB_0191435 antikoerper, MIP224 antikoerper, RPT3 antikoerper, S6 antikoerper, TBP-7 antikoerper, TBP7 antikoerper, CIP21 antikoerper, Tbp7 antikoerper, 26S protease regulatory subunit 6B antikoerper, regulatory particle, ATPase-like-3 antikoerper, 26S proteasome regulatory subunit 6B antikoerper, proteasome 26S subunit, ATPase 4 antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase, 4 antikoerper, LOC732870 antikoerper, rpt-3 antikoerper, ATEG_04674 antikoerper, LELG_01296 antikoerper, HCAG_00039 antikoerper, LOC5568998 antikoerper, GL50803_7950 antikoerper, EDI_044950 antikoerper, AOR_1_1218154 antikoerper, PTRG_03339 antikoerper, psmC4 antikoerper, prs6b antikoerper, LOC100381342 antikoerper, psmc4 antikoerper, PSMC4 antikoerper, Psmc4 antikoerper

Hintergrund:

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Gene: PSMC4

Molekulargewicht: 47kDa

Gen-ID: 5704

UniProt: P43686

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway