PSMC2 Antikörper (Internal Region)

Produktnummer ABIN6264479

Produktdetails anti-PSMC2 Antikörper

Target: PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PSMC2 Antibody detects endogenous levels of total PSMC2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSMC2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PSMC2

Target: PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))

Andere Bezeichnung: PSMC2 (PSMC2 Produkte)

Synonyme: xMSS1 antikoerper, psmc2 antikoerper, DDBDRAFT_0168337 antikoerper, DDBDRAFT_0232966 antikoerper, DDB_0168337 antikoerper, DDB_0232966 antikoerper, MSS1 antikoerper, Nbla10058 antikoerper, S7 antikoerper, NCU02840.1 antikoerper, zgc:63995 antikoerper, proteasome 26S subunit, ATPase 2 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 2 antikoerper, 26S protease regulatory subunit 7 antikoerper, proteasome 26S subunit, ATPase 2 antikoerper, regulatory particle, ATPase-like-1 antikoerper, psmc2.L antikoerper, psmc2 antikoerper, psmC2 antikoerper, PSMC2 antikoerper, rpt-1 antikoerper, GL50803_21331 antikoerper, EHI_080890 antikoerper, UREG_01412 antikoerper, PITG_10169 antikoerper, Psmc2 antikoerper, GL50803_86683 antikoerper, Tsp_09237 antikoerper

Hintergrund:

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Gene: PSMC2

Molekulargewicht: 48kDa

Gen-ID: 5701

UniProt: P35998

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway