PSMB9 Antikörper (Internal Region)

Produktnummer ABIN6264478

Produktdetails anti-PSMB9 Antikörper

Target: PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: Proteasome 20S LMP2 Antibody detects endogenous levels of total Proteasome 20S LMP2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Proteasome 20S LMP2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-PSMB9 Antikörper (ABIN6264478)

Liu, Wu, Zhu, Li, Liu: "IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species." in: International immunopharmacology, Vol. 48, pp. 76-83, (2018) (PubMed).

Details zu PSMB9

Target: PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))

Andere Bezeichnung: PSMB9 (PSMB9 Produkte)

Synonyme: LMP2 antikoerper, ring12 antikoerper, MHC-linked antikoerper, psmb9b antikoerper, lmp2 antikoerper, lmp2b antikoerper, psmb9 antikoerper, Lmp-2 antikoerper, Lmp2 antikoerper, PSMB6i antikoerper, RING12 antikoerper, beta1i antikoerper, psmb9-A antikoerper, macropain antikoerper, prosome antikoerper, wu:fa66f04 antikoerper, wu:fj22d05 antikoerper, zgc:91842 antikoerper, psmb9a antikoerper, proteasome subunit beta 9 antikoerper, LMP2 antikoerper, proteasome subunit beta type-9b antikoerper, proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) antikoerper, proteasome subunit beta 9 S homeolog antikoerper, proteasome subunit beta 9a antikoerper, proteasome (prosome, macropain) subunit, beta type, 9a antikoerper, psmb9 antikoerper, PSMB9 antikoerper, psmb9-b antikoerper, Psmb9 antikoerper, psmb9.S antikoerper, psmb9a antikoerper

Hintergrund:

Description: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic  pH . The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.

Gene: PSMB9

Molekulargewicht: 23kDa

Gen-ID: 5698

UniProt: P28065

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA