PSMB5 Antikörper (C-Term)

Produktnummer ABIN6264477

Produktdetails anti-PSMB5 Antikörper

Target: PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: PSMB5 Antibody detects endogenous levels of total PSMB5.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSMB5, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PSMB5

Target: PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))

Andere Bezeichnung: PSMB5 (PSMB5 Produkte)

Synonyme: LMPX antikoerper, MB1 antikoerper, X antikoerper, etID309919.2 antikoerper, fb59c07 antikoerper, si:zc14a17.13 antikoerper, wu:fb59c07 antikoerper, x antikoerper, zgc:86820 antikoerper, proteasome subunit beta 5 antikoerper, proteasome (prosome, macropain) subunit, beta type 5 antikoerper, proteasome subunit beta 5 L homeolog antikoerper, proteasome (prosome, macropain) subunit, beta type, 5 antikoerper, PSMB5 antikoerper, psmb5 antikoerper, Psmb5 antikoerper, psmb5.L antikoerper

Hintergrund:

Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.

Gene: PSMB5

Molekulargewicht: 28kDa

Gen-ID: 5693

UniProt: P28074

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA