PRMT7 Antikörper (Internal Region)

Produktnummer ABIN6264434

Produktdetails anti-PRMT7 Antikörper

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PRMT7 Antibody detects endogenous levels of total PRMT7.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PRMT7, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Andere Bezeichnung: PRMT7 (PRMT7 Produkte)

Synonyme: ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 7 antikoerper, ATPRMT7 antikoerper, DL4310W antikoerper, FCAALL.195 antikoerper, protein arginine methyltransferase 7 antikoerper, RGD1304869 antikoerper, 4933402B05Rik antikoerper, BC006705 antikoerper, zgc:66172 antikoerper, protein arginine methyltransferase 7 antikoerper, protein arginine methyltransferase 7 L homeolog antikoerper, protein arginine N-methyltransferase 7 antikoerper, Protein arginine N-methyltransferase 7 antikoerper, PRMT7 antikoerper, Prmt7 antikoerper, prmt7.L antikoerper, prmt7 antikoerper, prmt-7 antikoerper

Hintergrund:

Description: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.

Gene: PRMT7

Molekulargewicht: 78 kDa

Gen-ID: 54496

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization