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PRKACB Antikörper (C-Term)

PRKACB Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264422
  • Target Alle PRKACB Antikörper anzeigen
    PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
    Bindungsspezifität
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 58
    • 26
    • 18
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 56
    • 2
    Kaninchen
    Klonalität
    • 56
    • 2
    Polyklonal
    Konjugat
    • 25
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRKACB Antikörper ist unkonjugiert
    Applikation
    • 36
    • 33
    • 17
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    PKA beta Antibody detects endogenous levels of total PKA beta.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PKA beta, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PRKACB Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
    Andere Bezeichnung
    PRKACB (PRKACB Produkte)
    Synonyme
    PKACB antikoerper, XPKAbeta antikoerper, kin-1 antikoerper, pkacb antikoerper, prkacba antikoerper, PRKACB antikoerper, prkacb antikoerper, wu:fz54b03 antikoerper, zgc:110804 antikoerper, Pkacb antikoerper, protein kinase cAMP-activated catalytic subunit beta antikoerper, protein kinase cAMP-activated catalytic subunit beta S homeolog antikoerper, protein kinase, cAMP-dependent, catalytic, beta antikoerper, protein kinase, cAMP-dependent, catalytic, beta b antikoerper, protein kinase, cAMP dependent, catalytic, beta antikoerper, PRKACB antikoerper, prkacb.S antikoerper, prkacb antikoerper, Prkacb antikoerper, prkacbb antikoerper
    Hintergrund

    Description: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (PubMed:12420224, PubMed:21423175). Phosphorylates GPKOW which regulates its ability to bind RNA (PubMed:21880142).

    Gene: PRKACB

    Molekulargewicht
    40kDa
    Gen-ID
    5567
    UniProt
    P22694
    Pathways
    AMPK Signaling, Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism
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