PPP2CA Antikörper (C-Term)

Produktnummer ABIN6264391

Produktdetails anti-PPP2CA Antikörper

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2CA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PP2A-alpha Antibody detects endogenous levels of total PP2A-alpha.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PP2A-alpha, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Andere Bezeichnung: PPP2CA (PPP2CA Produkte)

Synonyme: PP2Ac antikoerper, PP2CA antikoerper, PP2Calpha antikoerper, RP-C antikoerper, PP2A antikoerper, R75353 antikoerper, Pp2a1 antikoerper, pp2ac antikoerper, zgc:110641 antikoerper, protein phosphatase 2 catalytic subunit alpha antikoerper, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antikoerper, protein phosphatase 2, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 2 catalytic subunit alpha L homeolog antikoerper, protein phosphatase 2, catalytic subunit, beta isozyme antikoerper, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antikoerper, PPP2CA antikoerper, Ppp2ca antikoerper, ppp2ca.L antikoerper, ppp2cb antikoerper, LOC471633 antikoerper, ppp2ca antikoerper

Hintergrund:

Description: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Gene: PPP2CA

Molekulargewicht: 36 kDa

Gen-ID: 5515

UniProt: P67775

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades