POLR2E Antikörper (Internal Region)

Produktnummer ABIN6264345

Produktdetails anti-POLR2E Antikörper

Target: POLR2E (Polymerase (RNA) II (DNA Directed) Polypeptide E, 25kDa (POLR2E))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: POLR2E Antibody detects endogenous levels of total POLR2E.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human POLR2E, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu POLR2E

Target: POLR2E (Polymerase (RNA) II (DNA Directed) Polypeptide E, 25kDa (POLR2E))

Andere Bezeichnung: POLR2E (POLR2E Produkte)

Synonyme: MGC68604 antikoerper, polr2e antikoerper, wu:fk97g10 antikoerper, zgc:101098 antikoerper, 2410021N14Rik antikoerper, 25kDa antikoerper, AW208866 antikoerper, RPB5 antikoerper, XAP4 antikoerper, RPABC1 antikoerper, hRPB25 antikoerper, hsRPB5 antikoerper, polymerase (RNA) II (DNA directed) polypeptide E, 25kDa S homeolog antikoerper, RNA polymerase II subunit E antikoerper, polymerase (RNA) II (DNA directed) polypeptide E, b antikoerper, polymerase (RNA) II (DNA directed) polypeptide E, 25kDa antikoerper, polymerase (RNA) II (DNA directed) polypeptide E antikoerper, DNA-directed RNA polymerases I, II, and III subunit RPABC1 antikoerper, polr2e.S antikoerper, POLR2E antikoerper, polr2eb antikoerper, polr2e antikoerper, Polr2e antikoerper, rpb-5 antikoerper

Hintergrund:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity).

Gene: POLR2E

Molekulargewicht: 24kDa

Gen-ID: 5434

UniProt: P19388

Pathways: Regulatorische RNA Pathways