P4HTM Antikörper (Internal Region)

Produktnummer ABIN6263968

Produktdetails anti-P4HTM Antikörper

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P4HTM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: P4HTM Antibody detects endogenous levels of total P4HTM.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human P4HTM, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu P4HTM

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Andere Bezeichnung: P4HTM (P4HTM Produkte)

Synonyme: Ph-4 antikoerper, RGD1311848 antikoerper, EGLN4 antikoerper, HIFPH4 antikoerper, P4H-TM antikoerper, PH-4 antikoerper, PH4 antikoerper, PHD4 antikoerper, 4933406E20Rik antikoerper, AI853847 antikoerper, BB128974 antikoerper, prolyl 4-hydroxylase, transmembrane antikoerper, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) antikoerper, shisa family member 5 antikoerper, P4htm antikoerper, P4HTM antikoerper, SHISA5 antikoerper

Hintergrund:

Description: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Gene: P4HTM

Molekulargewicht: 57 kDa

Gen-ID: 54681

UniProt: Q9NXG6